ABSTRACT
Pulmonary fluid refers to a thin and continuous liquid layer mainly consisting of airway mucus and lining liquid on the inner surface of alveoli, which is essential for maintaining a healthy lung. The clinical significance of rheological properties of pulmonary fluid in airway stability, pulmonary barrier and clearance functions, ventilator induced lung injury and surfactant replacement therapy in infant respiratory distress syndrome was introduced in this paper. Furthermore, a variety of classical methods for measuring surface tension and liquid viscosity, such as Langmuir-Wilhelmy balance, captive bubble method, glass capillary viscometer and rotational viscometer, and emerging techniques (e.g. particle tracking microrheometer and axisymmetric drop shape analysis) were reviewed, and their advantages and drawbacks were also compared, in order to provide an important reference for the assisted diagnosis and treatment of lung diseases in clinical practice.
ABSTRACT
According to the clinical requirements of cardiopulmonary bypass surgery, this paper established a simulation system for cardiac surgery which consists of venous reservoir, variable balance chamber, blood suction bag, ventricle suction bag, resistance valves, pressure gauges and tubings. Using the proposed system, perfusionists can mimic the implementation of pre-established surgery strategy, predict various abnormal conditions in the operation, and accordingly take the urgent actions so as to improve the success rate of surgery and to ensure the safety of patients.
Subject(s)
Humans , Cardiac Surgical Procedures , Cardiopulmonary Bypass , Catheters, Indwelling , Heart , SuctionABSTRACT
Using extracorporeal circulation for cardiopulmonary bypass is the first step for the successful cardiac surgery, and the blood pump is the key component in extracorporeal circulation devices, the control and measurement of mechanical-fluid parameters such as flow rate and pressure are very important to guarantee the successful cardiac surgery. This paper reviews several control methods of the blood pump based on the flow rate/pressure, heart rate, ventricular work and blood assist index, and also discusses the direct and indirect measurements of the flow rate and pressure. This review concludes with the main possible trends for the further development of the blood pump control and testing methods.
Subject(s)
Equipment Design , Extracorporeal Circulation , Heart-Assist DevicesABSTRACT
This paper mainly studies the driving system of centrifugal blood pump for extracorporeal circulation, with the core being disc magnetic coupling. Structure parameters of disc magnetic coupling are related to the ability of transferring magnetic torque. Therefore, it is necessary to carry out disc magnetic coupling permanent magnet pole number (n), air gap length (L(g)), permanent magnet thickness (L(m)), permanent magnet body inside diameter (R(i)) and outside diameter (R(o)), etc. thoroughly. This paper adopts the three-dimensional static magnetic field edge element method of Ansys for numerical calculation, and analyses the relations of magnetic coupling each parameter to transmission magnetic torque. It provides a good theory basis and calculation method for further optimization of the disc magnetic coupling.
Subject(s)
Extracorporeal Circulation , Magnetic Fields , Magnetics , TorqueABSTRACT
This paper is aimed to study the optimal selection of structure of vaneless centrifugal blood pump. The optimal objective is determined according to requirements of clinical use. Possible schemes are generally worked out based on structural feature of vaneless centrifugal blood pump. The optimal structure is selected from possible schemes with constraints on blood perfusion and blood damage indexes. Using an optimal selection method one can find the optimum structure scheme from possible schemes effectively. The results of numerical simulation of optimal blood pump showed that the method of constraints of blood perfusion and blood damage is competent for the requirements of selection of the optimal blood pumps.
Subject(s)
Blood Flow Velocity , Centrifugation , Equipment Design , Extracorporeal Circulation , Heart-Assist Devices , Hemolysis , Hydrodynamics , Perfusion , Prosthesis DesignABSTRACT
An impeller plays a significant role in the non-invasive ventilator. This paper shows a model of impeller for noninvasive ventilator established with the software Solidworks. The model was studied for feasibility based on ANSYS. Then stress and strain of the impeller were discussed under the external loads. The results of the analysis provided verification for the reliable design of impellers.
Subject(s)
Humans , Equipment Design , Respiration, Artificial , Software , Stress, Mechanical , Ventilators, MechanicalABSTRACT
In view of the problem of TCM diagnosis, grey relational analysis and fuzzy cluster are applied to TCM diagnosis of hepatocirrhosis and are presented in this paper. The validity of the two methods has been assessed through 900 cases in Shanghai. The results are in good agreement with the diagnosis of hepatocirrhosis made by the expert group, thus showing the fuzzy technology is of significance to the development of TCM modernization in an objective way.
Subject(s)
Humans , Diagnosis, Computer-Assisted , Diagnosis, Differential , Fuzzy Logic , Hepatitis B, Chronic , Liver Cirrhosis , Diagnosis , Medicine, Chinese Traditional , Methods , Reference StandardsABSTRACT
By dynamical collecting respirator's gas press signal on line and drawing gas press signal wave,this system can measure respirator's press values and analyze press's stability. The system can be used as a teaching demonstration system to display respirator's working status for students.
ABSTRACT
Sleep apnea syndrome(SAS) and its harm to the health are briefly introduced,the review on history and classification of sleep non-invasive ventilator is presented,and therapy mechanism of CPAP on SAS is described.Furthermore,the specifications of three popular CPAP in the market are compared and some new technologies of CPAP are discussed.